These are précis of a few books/articles discussing the dopamine hypothesis in schizophrenia. Apparently caffeine, both my nectar and nemesis, works on these receptors when consumed. I kept wondering why I feel better and a little more crazy for the first slough after the high passes.

https://www.sciencedirect.com/topics/neuroscience/dopamine-hypothesis-of-schizophrenia#:~:text=The%20dopamine%20hypothesis%20of%20schizophrenia,to%20hypofunctionality%20of%20dopamine%20D1

And a notable book:

https://www.sciencedirect.com/book/9780128018293/the-neurobiology-of-schizophrenia

A Huberman Lab YouTube vid discusses dopaminergic processes in a wide range of activities from exercise to substance use and abuse. Dr. Huberman also delineates the when, how and why of managing your dopamine highs and troughs. See below.